Wrinkles around the mouth – also known as smile lines – are a natural sign of aging that makes the face look older and less vibrant. Fortunately, there are now many effective methods to remove wrinkles around the mouth, from home remedies to modern cosmetic technology. In this article, HBio Clinic introduces 7 of the most popular ways to remove wrinkles around the mouth today, helping you choose the right method to maintain youthful and radiant skin.
7 Effective Ways to Improve Wrinkles Around the Mouth
When researching how to remove wrinkles around the mouth, the first thing you need to do is clearly define your goals and current skin condition. Each method of treating wrinkles around the mouth will yield different results depending on the degree of skin aging. For mild wrinkles, non-invasive methods can be applied; for deep wrinkles, more specialized procedures will bring more noticeable results.
Choosing the right method to remove wrinkles around the mouth helps you achieve high effectiveness and avoid risks during treatment.
1. Facelift Surgery
Facelift surgery is a highly invasive method that removes sagging skin, tightens soft tissue, and comprehensively reduces wrinkles around the mouth. Not only does it improve wrinkles around the mouth, but this technique also rejuvenates the overall face when combined with eyebrow lifting, neck lifting, or eyelid surgery.
Advantages
- Long-lasting results (7–12 years), comprehensive facial improvement.
- Eliminates even deep wrinkles and severe sagging – something that non-invasive methods cannot completely address.
- Noticeably younger-looking face after just one procedure.
Disadvantages
- Highly invasive, requires a recovery time of 2–4 weeks.
- High cost.
- Requires an experienced cosmetic surgeon to avoid complications.
Estimated cost: 50,000,000 – 120,000,000 VND depending on the skin tightening technique (SMAS, endoscopic, combined thread lifting, etc.)

2. Using Dermal Fillers
Filler injections are a method of filling in wrinkles caused by tissue loss and loss of skin elasticity. Fillers help “lift” deep smile lines to a balanced level, providing an immediate rejuvenating effect.
Advantages
- Immediate results after injection, no downtime required.
- Excellent for treating shallow to medium wrinkles.
- Quick procedure time (10–15 minutes).
- Minimal pain, extremely safe if using genuine fillers.
Disadvantages
- Not suitable for very deep wrinkles with significant sagging skin.
- Results last 8–18 months depending on the type of filler.
- Risk of complications if injection is performed incorrectly (lumps, vascular occlusion).
Estimated cost: 2,000,000 – 10,000,000 VND / 1ml depending on the filler brand (Juvederm, Restylane, Belotero…).

3. Botox® Injections
Botox® helps relax the muscle groups that create dynamic wrinkles around the mouth. While Botox alone isn’t enough to erase deep wrinkles, combining it with fillers provides optimal results.
Advantages
- Significantly reduces dynamic wrinkles.
- Quick procedure, minimal pain, no downtime.
- Results visible after 3–7 days.
Disadvantages
- Not suitable for deep static wrinkles.
- Results last approximately 3–6 months, requiring repeat injections.
- Incorrect injection technique can cause facial asymmetry and an unnatural smile.
Estimated cost: 1,500,000 – 6,000,000 VND depending on dose and injection area.

4. Laser Skin Resurfacing
Fractional CO2, Erbium, or non-ablative lasers stimulate collagen regeneration, reduce wrinkles, and improve skin texture around the mouth.
Advantages
- Strongly stimulates collagen production, rejuvenating the entire face.
- Reduces wrinkles, minimizes pores, and brightens skin.
- Suitable for shallow to moderate wrinkles.
Disadvantages
- Skin redness for a few days after treatment.
- Requires 1–3 sessions for best results.
- Strict sun protection is necessary.
Estimated cost: 2,000,000 – 8,000,000 VND/session

5. Light Therapy (LED Light Therapy)
Light therapy uses different wavelengths to stimulate cell regeneration, especially red light which helps increase collagen production and reduce wrinkles around the mouth. While not providing immediate results, it’s an excellent complementary method to other skin rejuvenation treatments, helping to maintain long-lasting effects.
Advantages
- Absolutely safe, suitable for all skin types.
- Supports collagen production, maintaining the results of other methods.
- Painless, no downtime required.
Disadvantages
- Slow results, cannot remove deep wrinkles.
- Requires multiple sessions.
Estimated cost: 200,000 – 600,000 VND/session

6. Chemical Peel
Chemical peeling is a method of removing wrinkles around the mouth that is suitable for shallow wrinkles. A specialized acid solution is applied to the skin to remove dead cells and stimulate the regeneration of new skin. After treatment, the skin becomes brighter, smoother, firmer, and wrinkles around the mouth are noticeably reduced.
Advantages
- Skin is brighter and smoother after 3-7 days.
- Helps treat shallow wrinkles and dull skin.
- Lower cost than high-tech methods.
Disadvantages
- Not suitable for deep wrinkles.
- Requires multiple maintenance sessions.
- May cause irritation if self-peel at home is not done correctly.
Estimated cost: 500,000 – 2,000,000 VND/session

7. Microneedling
Microneedling – also known as collagen induction therapy – is a gentle, minimally invasive way to reduce wrinkles around the mouth. This method creates micro-injuries on the skin to stimulate the natural production of collagen, filling in wrinkles and improving elasticity. When combined with serums or stem cells, the skin rejuvenation effect is even more pronounced.
Advantages
- Effectively improves mild wrinkles.
- Increases elasticity and smooths skin texture.
- Reasonable cost.
Disadvantages
- Not suitable for deep smile lines.
- May cause mild redness or burning after treatment.
- Requires strict post-treatment care (sun protection, moisturizing).
Estimated cost: 800,000 – 3,000,000 VND/session (higher if combined with PRP/stem cells)

Hbio Clinic – A reputable and high-quality address for removing wrinkles around the mouth in Hanoi
Hbio Clinic – Facial Skincare & Spa is a reputable address in Hanoi specializing in providing services to remove wrinkles around the mouth and rejuvenate the skin. Located at 24 Truong Han Sieu Street, Tran Hung Dao Ward, Hoan Kiem District, Hbio Clinic is easily accessible and equipped with modern facilities according to European standards. Our team of highly qualified doctors and technicians are committed to using genuine products, providing safe and effective solutions for reducing smile lines and improving the appearance of the area around the mouth.
Customers can contact us via phone number 0947 697 795 or visit our website hbioclinic.com.vn for detailed consultation.

Hbio Clinic’s wrinkle removal service for the corners of the mouth stands out with its systematic process: in-depth consultation, selection of the appropriate method (filler for smile lines, thread lift, or a combination), safe procedure, and post-treatment care to maintain long-lasting results. Before treatment, clients should review before-and-after photos of completed cases, inquire about costs, recovery time, and potential risks. Simultaneously, proper skin care, sun protection, and lifting of the mouth area after treatment will help maintain long-lasting and natural results.
Removing wrinkles around the mouth is not just about improving appearance, but also about boosting confidence and a youthful feeling every day. Depending on your needs and circumstances, you can apply methods ranging from home care and specialized products to modern aesthetic medical services. Carefully research each solution and choose a reputable clinic to achieve optimal, safe, and long-lasting results.

Tiếng Việt
Dr. Thai Nguyen – Founder and Medical Director of HBIO Clinic. As an expert in aesthetic dermatology, she regularly shares in-depth knowledge and practical experience to provide valuable and insightful information for those seeking better skin health.