Mesotherapy injections are becoming increasingly popular for skin improvement, but sometimes adverse reactions occur. Among these, post-mesotherapy granulomas are a common concern. This article from HBIO Clinic will analyze the causes, signs, and treatment of this condition.
What are post-mesotherapy granulomas?
Post-mesotherapy granulomas are small nodules that appear on the skin at the injection site. They may appear immediately after the treatment or develop gradually over the next few days. These granulomas vary in size and density, from large nodules easily felt to tiny ones difficult to see with the naked eye.

Common Reactions to Granulomas After Mesotherapy
Common manifestations of granulomas after Mesotherapy include:
- Swelling and tightness of the skin: Granulomas can cause swelling in the injected area, accompanied by pain and discomfort.
- Redness and burning sensation: In cases caused by bacteria, the skin around the granulomas is often red and hot.
- Fatigue: Some people may feel lethargic and uncomfortable, especially when granulomas appear in sensitive skin areas.
- Prolonged pain: Granulomas can cause persistent pain, especially in thin and sensitive skin areas.
Main Causes of Granulomas After Mesotherapy
Granulomas after Mesotherapy are one of the complications that people undergoing this beauty treatment may experience. Common causes of this phenomenon include:
Poor quality or unclear origin of Meso products
Using low-quality or unverified Meso compounds can negatively impact the skin. These products often contain impurities or fail to meet safety standards, stimulating inflammatory reactions and the formation of granulomas under the skin. To minimize risks, choose reputable aesthetic clinics and products with clear origins and licensed by health authorities.
Incorrect Meso injection technique
If the technician performing the injection does not adhere to sterile principles or performs the procedure inaccurately, the risk of infection at the injection site increases, leading to the formation of granulomas. Additionally, uneven distribution of the Meso substance also contributes to the appearance of granulomas.

Allergic reaction to Meso compounds
Some individuals with sensitive constitutions may experience allergic reactions to the components of Meso compounds, causing inflammation and the appearance of granulomas. The severity of the reaction depends on the individual’s immune system and sensitivity.
Weakened or overreacting immune system
The immune system plays a role in protecting the body against invading agents. When the immune system is weakened or overreacts to Meso compounds, inflammation can occur at the injection site, leading to the formation of granulomas.

How do granulomas after Mesotherapy affect the body?
Granulomas after Mesotherapy can cause serious complications, directly affecting health if not detected and treated early. The risk and severity depend on many factors such as injection technique, quality of Mesotherapy product, individual health condition, and other related factors.
Common reactions after Mesotherapy include: granulomas, swelling, pain at the injection site, infection, or skin irritation. If not properly cared for and treated, granulomas can damage skin tissue, even leaving permanent scars. Injecting Mesotherapy in sensitive areas such as the eyes, ears, or nose carries the risk of serious harm and affecting the function of these organs.
Therefore, if you notice signs such as granulomas, redness, or discomfort after Mesotherapy, you should quickly consult a specialist at HBIO Clinic for timely treatment.

The Fastest Ways to Treat Granulomas After Meso Injections
When granulomas appear after a meso injection, timely treatment is crucial to avoid serious complications and protect the skin. There are several effective and quick treatment methods, including:
Surgical Treatment at HBIO Clinic
Visiting HBIO Clinic for treatment of granulomas after meso injections is an effective option for severe cases or those unresponsive to home care.
Here, specialist doctors will examine and assess the severity of the granulomas and apply modern surgical techniques, ensuring safety and minimizing the risk of complications. Treatment at a reputable medical facility helps the skin recover quickly and reduces the risk of scarring.

Home Treatment Measures
For mild cases of granulomas, patients can apply several home care measures. Using over-the-counter anti-inflammatory creams or gels can help reduce swelling, inflammation, and pain.
Cold compresses are a simple way to soothe the affected area. In addition, maintaining a diet rich in vitamins and nutrients supports the immune system and promotes skin healing. However, this measure is only applicable to mild cases and does not replace specialized medical treatment.
The above is important information about granulomas after Meso injections and effective treatment methods. Early recognition and proper application, combined with home care or medical intervention when necessary, will help protect the skin, reduce the risk of complications, and provide safe and long-lasting aesthetic results.

Tiếng Việt
Dr. Thai Nguyen – Founder and Medical Director of HBIO Clinic. As an expert in aesthetic dermatology, she regularly shares in-depth knowledge and practical experience to provide valuable and insightful information for those seeking better skin health.