With over 10 years of experience working with thousands of clients in the field of skin rejuvenation and non-surgical lifting, the team of experts at HBIO Clinic has noticed that many people are still quite unclear about what PLLA is and whether PLLA thread lifting is truly effective. In this article, HBIO Clinic will help you understand the mechanism of action, effectiveness, and things you need to know before undergoing the procedure.

What is PLLA?
PLLA stands for Poly-L-Lactic Acid, a bioactive compound that stimulates the natural production of collagen under the skin. This ingredient has been used in medicine for many years due to its high biocompatibility and ability to safely decompose in the body.
In aesthetics, PLLA is considered a “helper” for skin rejuvenation because it regenerates collagen from within, rather than just temporarily filling the surface. When collagen production is stimulated, the skin gradually becomes firmer, smoother, and wrinkles are reduced.

This is also why PLLA thread lifting has become a popular rejuvenation trend in recent years.
How PLLA thread lifting works
PLLA thread lifting is a method of inserting biodegradable threads containing Poly-L-Lactic Acid under the skin to create a support framework for soft tissue and stimulate collagen production.
This is a popular rejuvenation solution because it is less invasive than surgery but still significantly improves the signs of aging.

After being implanted into the skin, PLLA threads work through two parallel mechanisms:
- Immediate skin tissue lifting: The threads form a support system that helps improve sagging skin to a certain extent immediately after the procedure.
- Long-term collagen stimulation: After lifting the skin tissue, the PLLA threads gradually dissolve and stimulate the body to produce new collagen and elastin. When the threads completely dissolve, a self-generated collagen network is formed, helping the skin maintain its natural firmness and elasticity for a long time.
Is PLLA thread implantation safe?
Yes, PLLA has been FDA (United States) certified for safety and effectiveness. The rate of allergic reactions or material rejection is almost zero because it is a completely biocompatible material.
However, any cosmetic procedure carries certain risks. After thread lifting, clients may experience mild swelling, bruising, tightness in the treated area, and possibly slight tingling. These are usually temporary reactions and will improve after a few days.

However, if the technique is incorrect or poor quality threads are used, some complications can occur such as thread displacement, skin bulges, infection, and facial asymmetry. Most of these cases are usually related to the practitioner’s skill or inadequate sterile procedures.
How long does the effect of PLLA thread lifting last?
This is the “valuable” point that makes PLLA threads far superior to older generation thread technologies.
Typically, PLLA threads need 12 to 18 months to completely dissolve in the body. However, thanks to their ability to continuously stimulate collagen production, the lifting and rejuvenating effects can last from 2-3 years, even up to 5 years depending on individual body type and aftercare.
Instructions for aftercare and recovery after PLLA thread lifting
For optimal thread stability and collagen stimulation, home care accounts for 30% of the success. Just remember these simple points:
- Hygiene and swelling reduction: Apply cold compresses for the first two days if there is mild swelling. Wash your face gently in an upward motion, avoiding harsh scrubbing.
- Sleeping position: Sleep on your back for the first 1-2 weeks, avoiding sleeping on your side with your cheek pressed against the pillow, which can dislodge the shaping threads.
- Nutrition: Avoid sticky rice, chicken, seafood, and water spinach for two weeks. Drink plenty of water and supplement with Vitamin C – this is an excellent “solvent” that helps PLLA threads stimulate collagen production twice as fast.

How much does PLLA thread lifting cost on the market?
The cost of PLLA thread lifting is not low and is usually higher than regular threads due to the high technical requirements and the ability to stimulate collagen production long-term.
Currently, the price usually ranges from 20 to 80 million VND depending on the treatment area, the number of threads used, and the degree of aging of each client.
Reputable PLLA thread lifting clinic trusted by customers
In aesthetic medicine, the technique used greatly determines the final result. Even a slight misplacement or incorrect tissue layer can directly affect the natural appearance of the face.
That’s why many clients choose HBIO Clinic for PLLA thread lifting.
Full certifications, transparent legal procedures
HBIO Clinic operates entirely under the official license of the Ministry of Health. We are committed to ensuring that 100% of the PLLA sutures used at our clinic are officially imported and have full CO/CQ certifications (certificates of origin and quality). Customers always have the right to check the barcode and labels of the sutures before proceeding with the treatment.

Experienced Medical Team
All thread lifting procedures at HBIO Clinic are performed by highly experienced doctors with a thorough understanding of facial muscle and blood vessel structure, ensuring the most natural and non-stiff rejuvenation results.
6-Step Sterile, Medical-Standard PLLA Thread Lifting Procedure
At HBIO Clinic, your safety is strictly protected through a closed-loop process:
- Examination and Design: Specialist doctors directly examine the skin, assess the degree of sagging, and create a personalized thread lifting plan for each face.
- Cleansing and Disinfection: Deep skin cleansing, exfoliation, and surface disinfection to ensure a sterile environment.
- Deep Anesthesia: Local anesthesia ensures complete comfort and minimal pain throughout the procedure.
- Thread Lifting Procedure: Doctors directly insert PLLA threads using advanced, precise, and quick techniques, minimizing damage.
- Soothe and regenerate: Cold electrophoresis immediately soothes the skin, followed by application of cell-restoring nutrients.
- Instructions and appointment scheduling: The doctor will provide home care instructions, issue a warranty card, and schedule a follow-up appointment.

Don’t let wrinkles and sagging facial muscles steal your confidence. Contact HBIO Clinic today to schedule a direct appointment with a doctor and receive a personalized PLLA rejuvenation plan!
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